Hexarelin

Experimental Growth-Hormone Secretagogue

Hexarelin is a synthetic growth-hormone secretagogue receptor agonist hexapeptide. It was studied experimentally by several routes but is not an approved self-administered peptide, and GH response does not establish parent exposure or long-term safety.

Pharmacokinetic model

A route-level PK model for hexarelin is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Experimental Growth-Hormone Secretagogue
Suggested cadence
once daily

Research behind this entry

  1. Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man Ghigo E, Arvat E, Gianotti L, Imbimbo BP, Lenaerts V, Deghenghi R, Camanni F · Journal of Clinical Endocrinology & Metabolism, 1994 DOI

    Twelve healthy volunteers received hexarelin intravenously, subcutaneously, intranasally, and orally. GH-response AUC suggested route differences, but the experiment measured pharmacodynamic GH release rather than…

1 published study referenced in the app, each with a plain-language summary.