Hawthorn
Crataegus preparations used historically for cardiovascular complaints. Some older adjunctive heart-failure trials reported symptom or physiologic signals, but studies used specific extracts and do not establish a mortality benefit or generic-product equivalence.
Pharmacokinetic model
A route-level PK model for hawthorn is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Herb
- Suggested cadence
- once daily
Research behind this entry
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Hawthorn extract for treating chronic heart failure
Cochrane review of older adjunctive trials found improvements in selected symptoms and physiologic outcomes, but studies were short, used specific standardized extracts, and were not designed to establish survival…
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Hawthorn (Crataegus spp.) in the treatment of cardiovascular disease
Narrative review described roughly 300 Crataegus species and heterogeneous clinical preparations. The verified record is PMID 22228939.
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Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.
This citation reports a human clinical study involving a formulation related to Hawthorn, not the isolated identity. The randomized trial used a hawthorn and vitamin-C beverage formulation; hawthorn-specific effects…
3 published studies referenced in the app, each with a plain-language summary.