Gymnema Sylvestre

Herb

Gymnema sylvestre botanical products marketed for glucose control and sweet-taste effects. Meta-analytic signals arise from small heterogeneous trials and should not be generalized across extracts or replace diabetes treatment.

Pharmacokinetic model

A route-level PK model for gymnema sylvestre is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Herb
Suggested cadence
once daily

Research behind this entry

  1. The effects of Gymnema Sylvestre supplementation on lipid profile, glycemic control, blood pressure, and anthropometric indices in adults: A systematic review and meta-analysis Zamani M, Ashtary-Larky D, Nosratabadi S, Bagheri R, Wong A, Rafiei MM, Asiabar MM, Khalili P, Asbaghi O, Davoodi SH · Phytotherapy Research, 2023 DOI

    Meta-analysis reported changes in selected glycemic and lipid outcomes, but trials were small and differed in populations, products, doses, and background treatment. Certainty and product generalizability remain limited.

  2. Gymnema sylvestre for Diabetes: From Traditional Herb to Future's Therapeutic Tiwari P, Ahmad K, Baig MH · Current Pharmaceutical Design, 2017 DOI

    Narrative review describes traditional use, chemistry, mechanisms, and early clinical observations. It is not a confirmatory efficacy trial and does not define standardized exposure.

  3. Comparative Effects of Gymnema sylvestre and Berberine on Adipokines, Body Composition, and Metabolic Parameters in Obese Patients: A Randomized Study. Bandala C, Carro-Rodríguez J, Cárdenas-Rodríguez N, Peña-Montero I, Gómez-López M, Hernández-Roldán AP, Huerta-Cruz JC, Muñoz-González F, Ignacio-Mejía I, Domínguez B, Lara-Padilla E · Nutrients, 2024 DOI

    This citation reports a human clinical study involving Gymnema Sylvestre. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.

3 published studies referenced in the app, each with a plain-language summary.