Gotu Kola
Centella asiatica botanical used in foods and traditional medicine and marketed for cognition or mood. A systematic review found no strong evidence for improvement across cognitive domains and highlighted weak product standardization and heterogeneous doses.
Pharmacokinetic model
A route-level PK model for gotu kola is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Herb
- Suggested cadence
- once daily
Research behind this entry
-
Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A Systematic Review and Meta-analysis
Review included five randomized trials of Centella alone and six of combination products. Meta-analysis found no significant advantage over placebo across cognitive domains; limited mood signals were reported, but most…
-
Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke
Small post-stroke comparative study evaluated two Centella extract doses against folic acid. It reported selected memory-domain improvements but was not placebo controlled; the later systematic review characterized it…
-
A Clinical Trial to Evaluate the Safety and Efficacy of Centella asiatica for Ulcerative Colitis.
This citation reports a human primary study involving Gotu Kola. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.
3 published studies referenced in the app, each with a plain-language summary.