GHK-Cu
Copper complex of the tripeptide glycyl-L-histidyl-L-lysine, commonly included in topical cosmetic products and also sold by unregulated suppliers for injection. Much of the cited wound-repair evidence is laboratory or animal research; controlled systemic human evidence and injectable safety data are limited.
Pharmacokinetic model
A route-level PK model for ghk-cu is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Copper Peptide
- Suggested cadence
- once daily
Research behind this entry
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In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds
GHK-Cu injected into implanted rat wound chambers increased several extracellular-matrix measures in a concentration-dependent manner. This animal wound model does not establish cosmetic efficacy, systemic benefits,…
1 published study referenced in the app, each with a plain-language summary.