Genistein
Isoflavone
Genistein is a soy-associated isoflavone and phytoestrogen. Purified aglycone, glycosides, soy foods, and mixed isoflavone products have different kinetics.
Pharmacokinetic model
A route-level PK model for genistein is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Isoflavone
- Suggested cadence
- once daily
Research behind this entry
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Safety, tolerability, and pharmacokinetics of single ascending doses of synthetic genistein (Bonistein) in healthy volunteers
Forty healthy volunteers received 30 to 300 mg of 99.4% synthetic genistein. Exposure was approximately dose-linear by AUC, but Cmax saturated at the highest dose and reported concentrations combine a highly specific…
1 published study referenced in the app, each with a plain-language summary.