Forskolin
Forskolin is a labdane diterpene isolated from Coleus forskohlii that directly activates adenylyl cyclase in experimental systems. Human supplement evidence mostly concerns standardized plant extracts, so those findings cannot be assumed to describe purified forskolin.
Pharmacokinetic model
A route-level PK model for forskolin is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Botanical Constituent
- Suggested cadence
- once daily
Research behind this entry
-
Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial
Thirty participants completed a 12-week randomized trial of 250 mg standardized Coleus forskohlii extract twice daily or placebo while both groups followed a hypocaloric diet. Insulin measures favored the extract, but…
1 published study referenced in the app, each with a plain-language summary.