Ferulic Acid

Phenolic Acid

Ferulic acid is a plant phenolic found in foods and botanical preparations. Free, bound, and formulation-derived exposure differ substantially.

Pharmacokinetic model

A route-level PK model for ferulic acid is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Phenolic Acid
Suggested cadence
once daily

Research behind this entry

  1. Pharmacokinetic comparison of the vasorelaxant compound ferulic acid following the administration of Guanxin II to healthy volunteers and patients with angina pectoris Li YH, Huang X, Wang Y, Fan R, Zhang HM, Ren P, Chen Y, Zhou HH, Liu ZQ, Liang YZ, Lu HM · Experimental and Therapeutic Medicine, 2013 DOI

    Serum ferulic acid was measured after oral Guanxin II, with several PK parameters differing between healthy participants and angina patients. Co-constituents and disease state prevent transfer to isolated ferulic acid.

1 published study referenced in the app, each with a plain-language summary.