Fenugreek

Herb

Trigonella foenum-graecum seed products marketed for metabolic, reproductive-hormone, and exercise-related claims. Meta-analyses report small or uncertain signals from a limited number of heterogeneous trials, so findings cannot be generalized across extracts.

Pharmacokinetic model

A route-level PK model for fenugreek is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Herb
Suggested cadence
once daily

Research behind this entry

  1. Effect of fenugreek extract supplement on testosterone levels in male: A meta-analysis of clinical trials Mansoori A, Hosseini S, Zilaee M, Hormoznejad R, Fathi M · Phytotherapy Research, 2020 DOI

    Random-effects meta-analysis pooled only four randomized trials and reported an increase in total serum testosterone. The small evidence base and differing extract formulations limit confidence and product-to-product…

  2. Fenugreek and Its Effects on Muscle Performance: A Systematic Review Albaker WI · Journal of Personalized Medicine, 2023 DOI

    Systematic review evaluated heterogeneous exercise and body-composition studies using different fenugreek preparations. It described possible performance signals but emphasized the need for larger, standardized trials…

  3. Investigating the Effectiveness of Fenugreek on the Quantity of Breast Milk and the Level of Prolactin in Mothers of Preterm Newborns: A Randomized Controlled Clinical Trial. Rouhi M, Hossieni MB, Khodaie L, Mohammad-Alizadeh-Charandabi S, Mirghafourvand M · Current drug research reviews, 2025 DOI

    This citation reports a human clinical study involving Fenugreek. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.

3 published studies referenced in the app, each with a plain-language summary.