Fadogia Agrestis
Botanical marketed mainly for aphrodisiac and testosterone-related claims. Available evidence is analytical or limited to rodents; there is no established human efficacy or exposure model, while animal studies raise liver, kidney, and testicular safety questions.
Pharmacokinetic model
A route-level PK model for fadogia agrestis is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Herb
- Suggested cadence
- once daily
Research behind this entry
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Quantification of Phenolic Compounds from Fadogia agrestis and Dietary Supplements using UHPLC-PDA-MS
Analytical study developed a constituent assay and examined 17 dietary supplements. Only 12 contained the targeted phenolic compounds, supporting concerns about identity and consistency rather than demonstrating human…
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Mode of cellular toxicity of aqueous extract of Fadogia agrestis stem in male rat liver and kidney
Rat study reported biochemical and tissue evidence consistent with liver and kidney toxicity after an aqueous stem extract. It cannot quantify human risk but contradicts treating the supplement as clinically established…
2 published studies referenced in the app, each with a plain-language summary.