Flavin Adenine Dinucleotide (FAD)
FAD is a redox coenzyme synthesized in cells from riboflavin through FMN. Dietary flavins are processed before cellular cofactor assembly, and an FAD measurement represents regulated endogenous pools rather than a simple circulating supplement parent.
Pharmacokinetic model
A route-level PK model for flavin adenine dinucleotide (fad) is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Endogenous Flavin Cofactor
- Suggested cadence
- once daily
Research behind this entry
-
Metabolism of injected flavins studied by using double-labeled [14C]flavin adenine dinucleotide and [14C, 32P]flavin mononucleotide
Double-labeled FAD and FMN injected into mice were rapidly hydrolyzed and their flavin moieties reincorporated into riboflavin, FMN, and FAD. The animal tracer experiment directly shows why intact injected FAD cannot be…
1 published study referenced in the app, each with a plain-language summary.