Ergocalciferol (Vitamin D2)

Vitamin

Ergocalciferol is vitamin D2, a fungal or plant-derived vitamin-D form. It is distinct from cholecalciferol (D3), and the two can differ in their effects on 25-hydroxyvitamin-D fractions. High-dose deficiency treatment should follow clinical monitoring.

Pharmacokinetic model

A route-level PK model for ergocalciferol (vitamin d2) is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Vitamin
Suggested cadence
once daily

Research behind this entry

  1. Bioavailability of vitamin D2 and D3 in healthy volunteers, a randomized placebo-controlled trial Lehmann U, Hirche F, Stangl GI, Hinz K, Westphal S, Dierkes J · Journal of Clinical Endocrinology & Metabolism, 2013 DOI

    Healthy volunteers received 50 micrograms/day vitamin D2, vitamin D3, or placebo for eight winter weeks. The trial separately measured 25(OH)D2, 25(OH)D3, total 25(OH)D, and PTH, demonstrating why D2 must not simply…

1 published study referenced in the app, each with a plain-language summary.