Diosmin
Flavonoid Glycoside
Diosmin is a diosmetin glycoside used in venous-disease products. Its absorption depends on microbial deglycosylation and formulation, so diosmin, diosmetin, and micronized flavonoid mixtures are not interchangeable.
Pharmacokinetic model
A route-level PK model for diosmin is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Flavonoid Glycoside
- Suggested cadence
- once daily
Research behind this entry
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Pharmacokinetics and metabolism of oral diosmin in healthy volunteers
After oral diosmin, investigators found no detectable parent in plasma but did detect its aglycone diosmetin, with a reported 26 to 43-hour elimination half-life. The study supports presystemic conversion, not a simple…
1 published study referenced in the app, each with a plain-language summary.