DHA

Omega-3 Fatty Acid

Docosahexaenoic acid, a long-chain omega-3 fatty acid concentrated in neural and retinal membrane phospholipids. Supplement bioavailability varies with ester form, food, emulsification, and source. Clinical effects depend on population and outcome; acute blood concentration is not a substitute for longer-term omega-3 status.

Pharmacokinetic model

A route-level PK model for dha is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Omega-3 Fatty Acid
Suggested cadence
once daily

Research behind this entry

  1. Health benefits of docosahexaenoic acid and its bioavailability: A review Li J, Pora BLR, Dong K, Hasjim J · Food Science and Nutrition, 2021 DOI

    Review describes life-stage roles, health-outcome evidence, and major determinants of supplement bioavailability. It notes discrepancies across claimed benefits and reports that phospholipid and triglyceride forms, food…

  2. Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases Sun GY, Simonyi A, Fritsche KL, Chuang DY, Hannink M, Gu Z, Greenlief CM, Yao JK, Lee JC, Beversdorf DQ · Prostaglandins, Leukotrienes and Essential Fatty Acids, 2018 DOI

    Mechanistic review discusses DHA in neural membranes and its enzymatic and oxidative products. It emphasizes that evidence for intake beyond normal nutritional requirements modifying many brain diseases is largely…

  3. Maternal Docosahexaenoic Acid Status during Pregnancy and Its Impact on Infant Neurodevelopment. Basak S, Mallick R, Duttaroy AK · Nutrients, 2020 DOI

    This citation reports a human clinical study involving DHA. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.

3 published studies referenced in the app, each with a plain-language summary.