Deglycyrrhizinated Licorice (DGL)
DGL is licorice extract processed to reduce, not necessarily eliminate, glycyrrhizin. Products differ in remaining glycyrrhizin and other flavonoids; results for a standardized branded extract do not transfer to every chewable, powder, or capsule.
Pharmacokinetic model
A route-level PK model for deglycyrrhizinated licorice (dgl) is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Botanical Extract
- Suggested cadence
- once daily
Research behind this entry
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Efficacy and Safety of GutGard in Managing Gastroesophageal Reflux-Related Symptoms: A Phase III, Single-Centre, Double-Blind, Randomized Placebo-Controlled Trial
A 28-day placebo-controlled trial evaluated a specific flavonoid-rich DGL extract standardized to at least 3.5 percent glabridin and at most 3 percent glycyrrhizin. Findings are product- and symptom-scale-specific and…
1 published study referenced in the app, each with a plain-language summary.