D-Chiro-Inositol
D-chiro-inositol is an inositol stereoisomer involved in insulin signaling and is sold alone or with myo-inositol. It is a distinct identity from myo-inositol; evidence from combination products cannot isolate its effect.
Pharmacokinetic model
A route-level PK model for d-chiro-inositol is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Inositol Isomer
- Suggested cadence
- once daily
Research behind this entry
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D-Chiro-inositol and its significance in polycystic ovary syndrome: a systematic review
This systematic review found promising metabolic and reproductive signals but emphasized that the clinical literature was small and heterogeneous. It does not provide pharmacokinetic parameters or make…
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Ovulatory and metabolic effects of D-chiro-inositol in the polycystic ovary syndrome
Forty-four women with PCOS were randomized to 1,200 mg daily or placebo for six to eight weeks. Several insulin, androgen, triglyceride, blood- pressure, and ovulation outcomes favored treatment, but the small,…
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Myo-inositol vs. D-chiro inositol in PCOS treatment.
This citation reports a human clinical study involving D-Chiro-Inositol. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.
3 published studies referenced in the app, each with a plain-language summary.