D-Aspartic Acid
D-aspartic acid is the D-enantiomer of aspartate and is sold for purported testosterone support. Controlled studies in resistance-trained men have not shown a testosterone increase at commonly studied doses, and a higher dose produced a short-term decrease in one small trial.
Pharmacokinetic model
A route-level PK model for d-aspartic acid is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Amino Acid Supplement
- Suggested cadence
- once daily
Research behind this entry
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Three and six grams supplementation of d-aspartic acid in resistance trained men
Twenty-four resistance-trained men were randomized to placebo, 3 g/day, or 6 g/day for 14 days. Three grams did not change testosterone; 6 g reduced total and calculated free testosterone. The short, small trial does…
1 published study referenced in the app, each with a plain-language summary.