Cocoa Flavanols
Standardized Cocoa Extract
Cocoa flavanols are a mixture that may include epicatechin, catechin, and procyanidins. Flavanol-standardized extracts are not equivalent to cocoa powder or dark chocolate, whose processing and calories vary.
Pharmacokinetic model
A route-level PK model for cocoa flavanols is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Standardized Cocoa Extract
- Suggested cadence
- once daily
Research behind this entry
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Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial
In COSMOS-Mind, 2,262 older adults entered a three-year factorial trial. Cocoa extract supplying 500 mg/day flavanols did not improve global cognition, memory, or executive function versus placebo, providing strong…
1 published study referenced in the app, each with a plain-language summary.