Choline Bitartrate

Choline Supplement

Water-soluble choline salt used in supplements. It remains separate from alpha-GPC, phosphatidylcholine, citicoline, and generic dietary choline because their salt mass, absorption, and metabolite profiles differ.

Pharmacokinetic model

A route-level PK model for choline bitartrate is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Choline Supplement
Suggested cadence
once daily

Research behind this entry

  1. Intake of 3 Eggs per Day When Compared to a Choline Bitartrate Supplement, Downregulates Cholesterol Synthesis without Changing the LDL/HDL Ratio Lemos BS, Medina-Vera I, Blesso CN, Fernandez ML · Nutrients, 2018 DOI

    Thirty healthy adults completed a crossover comparison of three eggs daily with choline bitartrate providing about 400 mg choline. Lipid and gene-expression responses differed, so results for whole eggs should not be…

  2. Plasma Kinetics of Choline and Choline Metabolites After A Single Dose of Krill Oil or Choline Bitartrate in Healthy Volunteers Modinger Y, Schon C, Wilhelm M, Hals PA · Nutrients, 2019 DOI

    Human single-dose comparison found similar free-choline exposure but different timing and metabolite profiles between phosphatidylcholine-rich krill oil and choline bitartrate. A parent-choline curve alone would omit…

2 published studies referenced in the app, each with a plain-language summary.