Chlorogenic Acid
Coffee Polyphenol
Chlorogenic acids are a family of caffeoylquinic and related acids found in coffee and plants. Product isomer composition and gut metabolism strongly affect exposure.
Pharmacokinetic model
A route-level PK model for chlorogenic acid is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Coffee Polyphenol
- Suggested cadence
- once daily
Research behind this entry
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Chlorogenic acids from green coffee extract are highly bioavailable in humans
Ten healthy adults consumed decaffeinated green-coffee extract containing 170 mg chlorogenic acids. Multiple caffeoylquinic acids and downstream phenolic metabolites appeared in plasma across 0.5 to 8 hours,…
1 published study referenced in the app, each with a plain-language summary.