Celastrus paniculatus

Ayurvedic Botanical

Celastrus paniculatus, sometimes called jyotishmati or intellect tree, is sold as seeds, oil, and extracts. Cognitive claims derive mainly from rodent studies and cannot establish human benefit or a safe retail dose.

Pharmacokinetic model

A route-level PK model for celastrus paniculatus is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Ayurvedic Botanical
Suggested cadence
once daily

Research behind this entry

  1. Nootropic activity of Celastrus paniculatus seed Bhanumathy M, Harish MS, Shivaprasad HN, Sushma G · Pharmaceutical Biology, 2010 DOI

    Aqueous seed extract was given orally at hundreds of mg/kg to rats and mice in maze and chemically induced amnesia tests. Behavioral and brain acetylcholinesterase changes were preclinical and do not establish human…

1 published study referenced in the app, each with a plain-language summary.