Cat's Claw
Botanical Extract
Cat's claw products may contain Uncaria tomentosa or U. guianensis and differ in oxindole-alkaloid chemotype. Evidence for one standardized extract cannot be generalized to all products.
Pharmacokinetic model
A route-level PK model for cat's claw is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Botanical Extract
- Suggested cadence
- once daily
Research behind this entry
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Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of Uncaria tomentosa for the treatment of rheumatoid arthritis
Forty patients received a defined pentacyclic-alkaloid U. tomentosa extract in a two-phase 52-week study. The narrow product and disease context cannot establish generic cat's-claw composition, dosing, or PK.
1 published study referenced in the app, each with a plain-language summary.