Carnosic Acid

Rosemary Diterpene

Carnosic acid is a phenolic diterpene found in rosemary and sage. Preclinical studies often use carnosic-acid-rich extracts rather than isolated carnosic acid, and do not establish clinical efficacy, a human dose, or product-independent pharmacokinetics.

Pharmacokinetic model

A route-level PK model for carnosic acid is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Rosemary Diterpene
Suggested cadence
once daily

Research behind this entry

  1. Carnosic acid-rich rosemary (Rosmarinus officinalis L.) leaf extract limits weight gain and improves cholesterol levels and glycaemia in mice on a high-fat diet Ibarra A, Cases J, Roller M, Chiralt-Boix A, Coussaert A, Ripoll C · British Journal of Nutrition, 2011 DOI

    A mouse high-fat-diet experiment tested a rosemary leaf extract enriched in carnosic acid and reported lower weight gain plus metabolic changes. It was not a human trial and did not isolate carnosic acid from the other…

1 published study referenced in the app, each with a plain-language summary.