Black Cohosh
Actaea racemosa preparations marketed mainly for menopausal symptoms. Product-specific trials and combination products cannot establish the effect of black cohosh alone, while adverse-event reviews highlight uncertain causality and the importance of product identity.
Pharmacokinetic model
A route-level PK model for black cohosh is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.
Key facts
- Category
- Herb
- Suggested cadence
- once daily
Research behind this entry
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Assessing the combined effects of Black Cohosh, Soy Isoflavones, and SDG Lignans on menopausal symptoms: a randomized, double-blind, placebo-controlled clinical trial
Randomized trial tested a combination of black cohosh, soy isoflavones, and lignans rather than black cohosh alone. Any reported symptom benefit therefore cannot isolate a black-cohosh effect or generalize across…
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Review of black cohosh-induced toxicity and adverse clinical effects
Review evaluated preclinical toxicity and adverse clinical reports, including liver-related concerns. Case reports and product heterogeneity limit causal inference, but the evidence supports caution and careful…
2 published studies referenced in the app, each with a plain-language summary.