Biotin (Vitamin B7)
Water-soluble B vitamin important for hair, skin, nails, and fatty acid metabolism. High doses can interfere with laboratory immunoassays.
Projected serum levels — 5k mcg (≈ 5 mg), once daily
Maintenance schedule: 5k mcg (≈ 5 mg) once daily (oral).
Modeled steady state after ~1 days: peak ≈ 1.3 mg, trough ≈ 0.001 mg body load. Population-based estimate over 15 days for a reference dose at a 70 kg reference body mass — the interactive app scales curves to your doses, timing, and body mass.
Key facts
- Category
- Vitamin
- Route modeled
- Oral
- Model confidence
- inferred
- Half-life
- 1.8 h
- Common dose
- 5k mcg (≈ 5 mg)
- Suggested maximum
- 10k mcg/day
- Reference dose range
- 2.5k–10k mcg (single dose)
- Suggested cadence
- once daily
- Validated against
- 5 mg oral — Cmax 0.065 mg/L at 1.8 h
Documented interactions
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warning
Levothyroxine (Synthroid) + Biotin (Vitamin B7)
High-dose biotin (> 5 mg) interferes with streptavidin-biotin immunoassays used for thyroid testing, causing falsely elevated T4/T3 and falsely suppressed TSH results.
Serum checks 1 modeled interaction pairings for biotin (vitamin b7) across your whole stack — absorption conflicts, enzyme inhibition, and nutrient depletion included.
Research behind this entry
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A review of the use of biotin for hair loss
Review found limited evidence supporting biotin for hair loss except in cases of actual biotin deficiency, noting most claims are not backed by controlled trials.
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Biotin interference with routine clinical immunoassays: understand the causes and mitigate the risks
Important safety review documenting how biotin supplementation can cause falsely abnormal lab results (including thyroid, cardiac, and hormone tests) by interfering with streptavidin-biotin immunoassays.
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Bioavailability of biotin given orally to humans in pharmacologic doses.
This citation reports a human clinical study involving Biotin (Vitamin B7). It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.
3 published studies referenced in the app, each with a plain-language summary.