Beetroot Extract

Supplement

Beet-derived products used mainly for dietary-nitrate and exercise or blood-pressure claims. Human evidence is strongest for quantified nitrate interventions, not for an unspecified amount of generic beetroot extract.

Pharmacokinetic model

A route-level PK model for beetroot extract is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Supplement
Suggested cadence
once daily

Research behind this entry

  1. The effect of beetroot inorganic nitrate supplementation on cardiovascular risk factors: A systematic review and meta-regression of randomized controlled trials Bahrami LS, Arabi SM, Feizy Z, Rezvani R · Nitric Oxide, 2021 DOI

    Review included 43 randomized trials qualitatively and 27 in meta-analysis. Cardiovascular findings were tied to quantified inorganic nitrate interventions and varied by outcome, dose, and population rather than proving…

  2. Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A · Hypertension, 2015 DOI

    Sixty-eight hypertensive adults received 250 mL/day nitrate-rich beetroot juice or nitrate-depleted placebo for four weeks. Blood pressure outcomes favored dietary nitrate, but the controlled nitrate dose should not be…

2 published studies referenced in the app, each with a plain-language summary.