Baicalin

Flavone Glucuronide

Baicalin is baicalein 7-O-glucuronide, a constituent of Scutellaria roots and a major conjugated metabolite after baicalein dosing. Baicalin, baicalein, and variable skullcap extracts must be treated as distinct interventions.

Pharmacokinetic model

A route-level PK model for baicalin is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Flavone Glucuronide
Suggested cadence
once daily

Research behind this entry

  1. Safety, tolerability, and pharmacokinetics of a single ascending dose of baicalein chewable tablets in healthy subjects Li M, Shi A, Pang H, Xue W, Li Y, Cao G, Yan B, Dong F, Li K, Xiao W, He G, Du G, Hu X · Journal of Ethnopharmacology, 2014 DOI

    Seventy-two healthy adults received baicalein chewable tablets, and baicalin was measured as a principal circulating metabolite. This is direct human baicalin measurement but not a trial of isolated baicalin; the…

1 published study referenced in the app, each with a plain-language summary.