Baicalein

Flavone

Baicalein is the aglycone flavone 5,6,7-trihydroxyflavone. It is distinct from its glucuronide baicalin and from multi-constituent Scutellaria extracts.

Pharmacokinetic model

A route-level PK model for baicalein is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Flavone
Suggested cadence
once daily

Research behind this entry

  1. Safety, tolerability, pharmacokinetics, and food effect of baicalein tablets in healthy Chinese subjects: A single-center, randomized, double-blind, placebo-controlled, single-dose phase I study Dong R, Li L, Gao H, Lou K, Luo H, Hao S, Yuan J, Liu Z · Journal of Ethnopharmacology, 2021 DOI

    Healthy participants received single baicalein tablet doses across a wide range. Parent half-life was approximately 7.8 to 14.9 hours, exposure was nonlinear, and food changed absorption; those product-specific data are…

1 published study referenced in the app, each with a plain-language summary.