Astragaloside IV

Triterpenoid Saponin

Astragaloside IV is a cycloartane-type saponin found in Astragalus species. Isolated astragaloside IV, Astragalus root extracts, total-astragalosides injections, and water-soluble derivatives are different interventions.

Pharmacokinetic model

A route-level PK model for astragaloside iv is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Triterpenoid Saponin
Suggested cadence
once daily

Research behind this entry

  1. Pharmacokinetics and tolerance of total astragalosides after intravenous infusion of astragalosides injection in healthy Chinese volunteers Xu M, Yin J, Xie L, Zhang J, Zou C, Zou J, Liu F, Ju W, Li P · Phytomedicine, 2013 DOI

    Healthy volunteers received 200 to 500 mL of a total-astragalosides intravenous product. Plasma astragaloside IV showed roughly linear exposure and a mean 2.14 to 2.69-hour half-life, but the mixture, IV route, and…

1 published study referenced in the app, each with a plain-language summary.