Artemisinin

Antimalarial Research Compoundprescription

Artemisinin is the parent endoperoxide from Artemisia annua. It is distinct from artesunate, artemether, and evidence-based combination antimalarial regimens.

Pharmacokinetic model

A route-level PK model for artemisinin is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Antimalarial Research Compound
Suggested cadence
once daily

Research behind this entry

  1. Artemisinin pharmacokinetics in healthy adults after 250, 500 and 1000 mg single oral doses Ashton M, Gordi T, Trinh NH, Nguyen VH, Nguyen DS, Nguyen TN, Dinh XH, Johansson M, Le DC · Biopharmaceutics and Drug Disposition, 1998 DOI

    Healthy adults received single 250, 500, or 1000 mg oral doses. The study supplies single-dose kinetics but cannot describe the marked exposure reduction documented during repeated treatment.

1 published study referenced in the app, each with a plain-language summary.