Andrographis

Herb

Andrographis paniculata preparations studied mainly for respiratory or inflammatory conditions. Evidence syntheses mix mechanistic, preclinical, single-extract, and combination-product data, limiting general claims.

Pharmacokinetic model

A route-level PK model for andrographis is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Herb
Suggested cadence
once daily

Research behind this entry

  1. Mechanistic Evidence of Andrographis paniculata and Other Herbal Medicines in the Treatment of Acute, Uncomplicated Respiratory Tract Infections Veldman LBM, Belt-Van Zoen E, Baars EW · Pharmaceuticals, 2023 DOI

    Systematic literature review and expert interviews considered several different herbal medicines. Mechanistic plausibility and heterogeneous clinical observations do not establish efficacy for generic Andrographis…

  2. Herbal Medicines for the Treatment of Active Ulcerative Colitis: A Systematic Review and Meta-Analysis Iyengar P, Godoy-Brewer G, Maniyar I, White J, Maas L, Parian AM, Limketkai B · Nutrients, 2024 DOI

    Review evaluated multiple herbal interventions for active ulcerative colitis, including specific Andrographis preparations. Small trials and intervention heterogeneity prevent treating the pooled evidence as a generic…

  3. Efficacy of Andrographis paniculata spray in acute pharyngitis: A randomized controlled trial. Okonogi R, Thampanya V, Okonogi S · Drug discoveries & therapeutics, 2023 DOI

    This citation reports a human clinical study involving Andrographis. It does not by itself establish a qualified dose, safety profile, efficacy claim, or pharmacokinetic route for this record.

3 published studies referenced in the app, each with a plain-language summary.