Anandamide (AEA)

Endocannabinoid

Anandamide is an endogenous N-acylethanolamine signaling lipid. It is not an approved supplement, and exogenous products lack established identity, route, dosing, and safety.

Pharmacokinetic model

A route-level PK model for anandamide (aea) is being prepared from published data. Dosing references, studies, and documented interactions are below; the app catalog is updated as models are validated.

Key facts

Category
Endocannabinoid
Suggested cadence
once daily

Research behind this entry

  1. Vascular effects of anandamide and N-acylvanillylamines in the human forearm and skin microcirculation Movahed P, Evilevitch V, Andersson TL, Jönsson BA, Wollmer P, Zygmunt PM, Högestätt ED · British Journal of Pharmacology, 2005 DOI

    Locally administered anandamide dilated human skin microvasculature but did not support a role as a circulating forearm vasoactive hormone. This local pharmacology study did not provide systemic PK.

1 published study referenced in the app, each with a plain-language summary.